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Cross-Reactivity of Canine MAGE-A with Hominid Monoclonal Antibody 6C1

Cross-Reactivity of Canine MAGE-A with Hominid Monoclonal Antibody 6C1

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A Preliminary Examine of the Cross-Reactivity of Canine MAGE-A with Hominid Monoclonal Antibody 6C1 in Canine Mammary Gland Tumors: An Enticing Goal for Most cancers Diagnostic, Prognostic and Immunotherapeutic Improvement in Canines

Melanoma-related antigen-A (MAGE-A), a household of most cancers/testis antigens, has been acknowledged as a possible goal molecule for most cancers immunotherapy.
Nonetheless, there was little or no data obtainable with regard to this antigen in canines. This examine aimed to research the expression of MAGE-A in canine mammary gland tumors (CMTs) utilizing immunohistochemistry and immunoblotting with human monoclonal MAGE-A antibody 6C1.
The current examine has offered proof of cross-reactivity of the canine MAGE-A expression with the human MAGE-A antibody in CMTs. The MAGE-A antigens had been expressed in moderate- and high-grade malignant CMTs (22.22%, 2/9), however no expression was noticed in benign CMTs.
The immunohistochemical staining of canine MAGE antigen in CMT cells confirmed nuclear and nuclear-cytoplasmic expression patterns that could be concerned with the mitotic cell division of tumor cells.
Molecular weights of the canine MAGE-A antigen introduced on this examine had been roughly 42-62 kDa, which had been near these of different earlier research involving people and canines.
The findings on this protein in CMTs may provide beneficial oncological data for the event of novel diagnostic, prognostic and immunotherapeutic tumor markers in veterinary medication.
Key phrases: canine mammary gland tumors; human monoclonal MAGE-A antibody 6C1; immunohistochemistry; melanoma-related antigen-A; tumor marker.
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MOUSE ANTI HUMAN CD163

MBS212351-02mg 0.2mg
EUR 550

MOUSE ANTI HUMAN CD163

MBS212351-5x02mg 5x0.2mg
EUR 2295

human anti-human CD163 mAb

E4A09C49 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Mouse Anti Human CD163: RPE

MBS225636-100Tests 100Tests
EUR 520

Mouse Anti Human CD163: RPE

MBS225636-5x100Tests 5x100Tests
EUR 2160

MOUSE ANTI HUMAN CD163: FITC

MBS225948-01mg 0.1mg
EUR 435

MOUSE ANTI HUMAN CD163: FITC

MBS225948-5x01mg 5x0.1mg
EUR 1785

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-48Tests 48 Tests Ask for price

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-96Tests 96 Tests
EUR 388

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-48T 48T
EUR 346.8

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-96T 96T
EUR 559.2

Human CD163 antigen(CD163)ISA kit

QY-E05066 96T
EUR 433.2

human CD163 antigen,CD163 LISA kit

201-12-0247 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

human CD163 antigen,CD163 ELISA kit

YLA0098HU-48T 48T Ask for price

human CD163 antigen,CD163 ELISA kit

YLA0098HU-96T 96T Ask for price

Human CD163 antigen,CD163 ELISA KIT

E0246Hu-1096T 10*96T
EUR 4122

Human CD163 antigen,CD163 ELISA KIT

E0246Hu-48wells 48 wells
EUR 300

Human CD163 antigen,CD163 ELISA KIT

E0246Hu-596T 5*96T
EUR 2061

Human CD163 antigen,CD163 ELISA KIT

E0246Hu-96wells 96 wells
EUR 458

Human CD163 Antigen (CD163) ELISA Kit

MBS9353075-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human CD163 Antigen (CD163) ELISA Kit

MBS9353075-48StripWells 48-Strip-Wells
EUR 550

Human CD163 Antigen (CD163) ELISA Kit

MBS9353075-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human CD163 Antigen (CD163) ELISA Kit

MBS9353075-96StripWells 96-Strip-Wells
EUR 765

Human CD163 antigen, CD163 ELISA Kit

MBS165165-10x96StripWells 10x96-Strip-Wells
EUR 3460

Human CD163 antigen, CD163 ELISA Kit

MBS165165-48StripWells 48-Strip-Wells
EUR 285

Human CD163 antigen, CD163 ELISA Kit

MBS165165-5x96StripWells 5x96-Strip-Wells
EUR 1750

Human CD163 antigen, CD163 ELISA Kit

MBS165165-96StripWells 96-Strip-Wells
EUR 425

Human CD163 Antigen, CD163 GENLISA ELISA

KBH0246 1 x 96 wells
EUR 286

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47162MH 25 µg
EUR 446.4

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47163MH 0.2 mg
EUR 1057.2

Mouse Anti Human CD163, APC Conjugated mAb

MBS9431893-100Tests 100Tests
EUR 520

Mouse Anti Human CD163, APC Conjugated mAb

MBS9431893-25Tests 25Tests
EUR 275

Mouse Anti Human CD163, APC Conjugated mAb

MBS9431893-5x100Tests 5x100Tests
EUR 2195

CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 2

SC308167 10 µg Ask for price

CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 1

SC117495 10 µg Ask for price

PE anti-human CD163

E16FHP163-025 25 tests
EUR 433.33
Description: Available in various conjugation types.

PE anti-human CD163

E16FHP163-100 100 tests
EUR 953.33
Description: Available in various conjugation types.

Anti-Human CD163 PE

MBS696987-100Tests 100Tests
EUR 415

Anti-Human CD163 PE

MBS696987-25Tests 25Tests
EUR 225

Anti-Human CD163 PE

MBS696987-5x100Tests 5x100Tests
EUR 1820

Anti-Human CD163 Antibody

101-M291 100 µg
EUR 399
Description: CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes.

APC anti-human CD163

E16FHA163-025 25 tests
EUR 520
Description: Available in various conjugation types.

APC anti-human CD163

E16FHA163-100 100 tests
EUR 1191.67
Description: Available in various conjugation types.

Anti-Human CD163 APC

MBS696989-100Tests 100Tests
EUR 480

Anti-Human CD163 APC

MBS696989-25Tests 25Tests
EUR 245

Anti-Human CD163 APC

MBS696989-5x100Tests 5x100Tests
EUR 2115

APC anti-human CD163

MBS9459445-100Tests 100Tests
EUR 655

APC anti-human CD163

MBS9459445-25Tests 25Tests
EUR 355

APC anti-human CD163

MBS9459445-5x100Tests 5x100Tests
EUR 2790

FITC anti-human CD163

E16FHF163-025 25 tests
EUR 520
Description: Available in various conjugation types.

FITC anti-human CD163

E16FHF163-100 100 tests
EUR 1191.67
Description: Available in various conjugation types.

Biotin anti-human CD163

E16FHB163-025U 25 μg
EUR 346.67
Description: Available in various conjugation types.

Biotin anti-human CD163

E16FHB163-100U 100 μg
EUR 780
Description: Available in various conjugation types.

Purified anti-human CD163

E16FHU163-100U 100 μg
EUR 433.33
Description: Available in various conjugation types.

CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 2

RG212754 10 µg Ask for price

CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 1

RG208557 10 µg Ask for price

Rabbit Anti Human CD163 Monoclonal Clone ABCC-3

IRBAHUCD163ABCC3C100UL each
EUR 496
Description: Rabbit Anti Human CD163 Monoclonal Clone ABCC-3

Recombinant Human CD163/CD163 Protein, His Tag

E40KMH346 20ug
EUR 495

CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 1

RC208557 10 µg Ask for price

CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 2

RC212754 10 µg Ask for price

Human CD163 Protein

E40KMPH6242 20ug
EUR 495

Recombinant Human CD163

MBS147285-0001mg 0.001mg
EUR 240

Recombinant Human CD163

MBS147285-0005mg 0.005mg
EUR 310

Recombinant Human CD163

MBS147285-005mg 0.05mg
EUR 1360

Recombinant Human CD163

MBS147285-5x005mg 5x0.05mg
EUR 5800

CD163 siRNA (Human)

MBS8229683-15nmol 15nmol
EUR 405

CD163 siRNA (Human)

MBS8229683-30nmol 30nmol
EUR 565

CD163 siRNA (Human)

MBS8229683-5x30nmol 5x30nmol
EUR 2450

Anti-Human CD163 Antibody (M130)

MBS1564482-01mg 0.1mg
EUR 340

Anti-Human CD163 Antibody (M130)

MBS1564482-5x01mg 5x0.1mg
EUR 1235

Anti-Human CD163 Antibody (AB101)

MBS1570008-01mg 0.1mg
EUR 405

Anti-Human CD163 Antibody (AB101)

MBS1570008-5x01mg 5x0.1mg
EUR 1520

PE-Cy7 anti-human CD163

E16FHN163-025 25 tests
EUR 650
Description: Available in various conjugation types.

PE-Cy7 anti-human CD163

E16FHN163-100 100 tests
EUR 1408.33
Description: Available in various conjugation types.

APC-Cy7 anti-human CD163

E16FHO163-025 25 tests
EUR 650
Description: Available in various conjugation types.

APC-Cy7 anti-human CD163

E16FHO163-100 100 tests
EUR 1408.33
Description: Available in various conjugation types.

PerCP-Cy5.5 anti-human CD163

E16FHS163-025 25 tests
EUR 541.67
Description: Available in various conjugation types.

PerCP-Cy5.5 anti-human CD163

E16FHS163-100 100 tests
EUR 1278.33
Description: Available in various conjugation types.

Anti-Human CD163 PE-Cyanine7

MBS696988-100Tests 100Tests
EUR 505

Anti-Human CD163 PE-Cyanine7

MBS696988-25Tests 25Tests
EUR 270

Anti-Human CD163 PE-Cyanine7

MBS696988-5x100Tests 5x100Tests
EUR 2220

Mouse Monoclonal anti-human CD163

hAP-0161 100ug
EUR 250

Mouse Monoclonal anti-human CD163

hAP-0161A 50ug
EUR 400

Human, Rat, Mouse CD163 antibody

P0405 100ul
EUR 150

Human CD163, Fc Tag

E24PHA282 50 μg
EUR 250

Human CD163, His Tag

E24PHA281 50 μg
EUR 250

Human CD163 ELISA Kit

EK5296 96 tests
EUR 599

Muscle biopsy in anti-neutrophil cytoplasmic antibody-associated vasculitis: diagnostic yield is dependent upon anti-neutrophil cytoplasmic antibody kind, intercourse and neutrophil depend

Targets: 
Examine aimed to look at the sensitivity of muscle biopsy (MB) in ANCA-associated vasculitis (AAV), determine components predicting MB positivity and assess the prognostic worth of a constructive MB.
Strategies: We performed a single-centre retrospective examine of AAV with an MB carried out at analysis. AAV classification [granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), eosinophilic granulomatosis with polyangiitis (EGPA)] adopted the European Medicines Company algorithm.
A logistic regression mannequin was used to determine the components related to MB positivity.
Survival curves had been generated utilizing the Kaplan-Meier technique.
Outcomes: Amongst 276 AAV sufferers (1995-2018), 101 had an MB. Seventy-eight sufferers had been included: 33 with GPA, 25 with MPA and 20 with EGPA.
MB samples had been constructive in 45 circumstances (58%): 17 GPA, 16 MPA and 12 EGPA. Univariate evaluation focussed on GPA and revealed that the MB yield was greater in females [22/31 (71%) vs 11/27 (41%); P = 0.02] and in anti-MPO sufferers [25/37 (68%) vs 6/19 (32%) for anti-PR3; P = 0.01].
By multivariate evaluation, three components predicted MB positivity: anti-MPO ANCA [odds ratio (OR) 10.67 (CI 2.09, 81.68)], feminine intercourse [OR 5.3 (CI 1.16, 32.35)] and neutrophil depend [OR 1.33 (CI 1.07, 1.8)].
MB positivity had no impression on relapse, dying or end-stage renal disease-free survival.
Conclusions: MB is a secure and environment friendly diagnostic instrument for AAV. Predictors of MB yield embrace ANCA kind, intercourse and neutrophil depend. MB can’t substitute for kidney biopsy when indicated, however needs to be thought of in different circumstances.
Key phrases: Churg–Strauss syndrome; Wegener’s granulomatosis; anti-neutrophil cytoplasm antibody; microscopic polyangiitis; muscle; vasculitis.
Molecular and structural foundation for Lewis glycan recognition by a cancer-targeting antibody
Immunotherapy has been profitable in treating many tumour varieties. The event of extra tumour-antigen binding monoclonal antibodies (mAbs) will assist broaden the vary of immunotherapeutic targets.
Lewis histo-blood group and associated glycans are overexpressed on many carcinomas, together with these of the colon, lung, breast, prostate and ovary, and may subsequently be selectively focused by mAbs.
Right here we study the molecular and structural foundation for recognition of prolonged Lea and Lexcontaining glycans by a chimeric mAb.
Each the murine (FG88.2) IgG3 and a chimeric (ch88.2) IgG1 mAb variants confirmed reactivity to colorectal most cancers cells resulting in considerably diminished cell viability.
We decided the X-ray construction of the unliganded ch88.2 fragment antigen-binding (Fab) containing two Fabs within the unit cell.
A mix of molecular docking, glycan grafting and molecular dynamics simulations predicts two distinct subsites for recognition of Lea and Lex trisaccharides.
Whereas mild chain residues had been completely used for Lea binding, recognition of Lex concerned each mild and heavy chain residues. An prolonged groove is predicted to accommodate the Lea-Lex hexasaccharide with adjoining subsites for every trisaccharide.
The molecular and structural particulars of the ch88.2 mAb introduced right here present perception into its cross-reactivity for varied Lea and Lexcontaining glycans. Moreover, the expected interactions with prolonged epitopes doubtless explains the selectivity of this antibody for concentrating on Lewis-positive tumours.
Key phrases: Carbohydrate-binding antibody; Lewis glycans; cancer-targeting antibody; molecular docking.

Mouse Anti-Rat Podoplanin

MBS690143-5x01mg 5x0.1mg
EUR 1725

Mouse Anti Human Podoplanin

MBS140296-0005mg 0.005mg
EUR 240

Mouse Anti Human Podoplanin

MBS140296-002mg 0.02mg
EUR 310

Mouse Anti Human Podoplanin

MBS140296-01mg 0.1mg
EUR 610

Mouse Anti Human Podoplanin

MBS140296-5x01mg 5x0.1mg
EUR 2405

MOUSE ANTI HUMAN PODOPLANIN

MBS212743-01mg 0.1mg
EUR 450

MOUSE ANTI HUMAN PODOPLANIN

MBS212743-5x01mg 5x0.1mg
EUR 1840

Hamster anti Podoplanin (mouse)

103-M40 100ug
EUR 297.6

Mouse Anti-Human Podoplanin

MBS690117-0025mg 0.025mg
EUR 310

Mouse Anti-Human Podoplanin

MBS690117-5x0025mg 5x0.025mg
EUR 1110

Mouse Anti-Human Podoplanin

MBS690586-01mg 0.1mg
EUR 450

Mouse Anti-Human Podoplanin

MBS690586-5x01mg 5x0.1mg
EUR 1725

Mouse Anti-Human Podoplanin

MBS690680-0025mg 0.025mg
EUR 310

Mouse Anti-Human Podoplanin

MBS690680-5x0025mg 5x0.025mg
EUR 1110

Mouse Anti-Human Podoplanin

MBS690759-01mg 0.1mg
EUR 450

Mouse Anti-Human Podoplanin

MBS690759-5x01mg 5x0.1mg
EUR 1725

Mouse Anti-Human Podoplanin

MBS690992-005mg 0.05mg
EUR 430

Mouse Anti-Human Podoplanin

MBS690992-5x005mg 5x0.05mg
EUR 1645

Mouse Anti-Human Podoplanin

MBS692357-005mg 0.05mg
EUR 450

Mouse Anti-Human Podoplanin

MBS692357-5x005mg 5x0.05mg
EUR 1725

Mouse Anti-Human Podoplanin

MBS692358-005mg 0.05mg
EUR 450

Mouse Anti-Human Podoplanin

MBS692358-5x005mg 5x0.05mg
EUR 1725

Mouse anti Podoplanin-Biotin (human)

101-MBi40 50ug
EUR 297.6

Hamster anti Podoplanin-Biotin (mouse)

103-MBi40 50ug
EUR 297.6

Podoplanin Mouse mAb

A18776 100μL
EUR 719.13

Mouse Anti Human Podoplanin clone P56F7AT

MBS146676-0005mg 0.005mg
EUR 240

Mouse Anti Human Podoplanin clone P56F7AT

MBS146676-002mg 0.02mg
EUR 310

Mouse Anti Human Podoplanin clone P56F7AT

MBS146676-01mg 0.1mg
EUR 610

Mouse Anti Human Podoplanin clone P56F7AT

MBS146676-5x01mg 5x0.1mg
EUR 2405

Mouse Podoplanin, soluble

MBS691731-0005mg 0.005mg
EUR 250

Mouse Podoplanin, soluble

MBS691731-5x0005mg 5x0.005mg
EUR 835

Anti-Human/Mouse PDPN/Podoplanin Antibody

MBS1569238-01mg 0.1mg
EUR 405

Anti-Human/Mouse PDPN/Podoplanin Antibody

MBS1569238-5x01mg 5x0.1mg
EUR 1520

Recombinant Mouse Podoplanin

MBS7610672-005mg 0.05mg
EUR 345

Recombinant Mouse Podoplanin

MBS7610672-02mg 0.2mg
EUR 635

Recombinant Mouse Podoplanin

MBS7610672-1mg 1mg
EUR 1800

Recombinant Mouse Podoplanin

MBS7610672-5x1mg 5x1mg
EUR 6955

Mouse Monoclonal anti-Rat Podoplanin Antibody

xAP-0897 100ug
EUR 280

Mouse Podoplanin ELISA kit

E01A24381 96T
EUR 700
Description: ELISA

Mouse Podoplanin ELISA kit

E03P0082-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit

E03P0082-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit

E03P0082-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA Kit

IMSPDPNKT each
EUR 752
Description: Mouse Podoplanin ELISA Kit

Mouse Podoplanin ELISA Kit

MBS725552-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Podoplanin ELISA Kit

MBS725552-48StripWells 48-Strip-Wells
EUR 485

Mouse Podoplanin ELISA Kit

MBS725552-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Podoplanin ELISA Kit

MBS725552-96StripWells 96-Strip-Wells
EUR 690

Mouse Podoplanin ELISA Kit

MBS2884556-10x96StripWells 10x96-Strip-Wells
EUR 4080

Mouse Podoplanin ELISA Kit

MBS2884556-48StripWells 48-Strip-Wells
EUR 390

Mouse Podoplanin ELISA Kit

MBS2884556-5x96StripWells 5x96-Strip-Wells
EUR 2220

Mouse Podoplanin ELISA Kit

MBS2884556-96StripWells 96-Strip-Wells
EUR 520

Hamster Anti-Mouse Podoplanin

MBS690646-01mg 0.1mg
EUR 450

Hamster Anti-Mouse Podoplanin

MBS690646-5x01mg 5x0.1mg
EUR 1725

Hamster Anti-Mouse Podoplanin

MBS690790-005mg 0.05mg
EUR 430

Hamster Anti-Mouse Podoplanin

MBS690790-5x005mg 5x0.05mg
EUR 1645

Anti-Mouse Podoplanin Antibody

103-M552 100 µg
EUR 399
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Through its association with CLEC2, Podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Mouse Podoplanin Antibody

103-PA40 200 µg
EUR 204.75
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Anti-Mouse Podoplanin Antibody

103-PA40S 100 µg
EUR 126
Description: Podoplanin, also known as glycoprotein 38 (gp38), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 38 kDa type I transmembrane sialoglycoprotein and member of the podoplanin family. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. The ECD contains abundant Ser/Thr residues as potential sites for Oglycosylation, and the cytoplasmic region contains putative sites for kinase C and cAMP phosphorylation. Mouse Podoplanin shares 77% and 46% aa sequence identity with rat and human Podoplanin, respectively. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells, and on numerous tumors including colorectal tumors, squamous cell carcinomas, testicular seminoma, and brain tumors. One study shows high expression of Podoplanin mRNA in placenta, lung, skeletal muscle, and heart, and weaker levels in brain, kidney, and liver. Podoplanin is the ligand for Ctype lectin like receptor 2 (CLEC2). Their association is dependent on sialic acid on Oglycans of Podoplanin. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Mouse Podoplanin (PDPN) Protein

20-abx650139
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Podoplanin (PDPN) Protein

abx694266-10nmol 10 nmol
EUR 700

Mouse Podoplanin (PDPN) Protein

abx694266-5nmol 5 nmol
EUR 462.5

Mouse Podoplanin (PDPN) Protein

abx650139-100g 100 µg
EUR 537.5

Mouse Podoplanin (PDPN) Protein

abx650139-10g 10 µg
EUR 212.5

Mouse Podoplanin (PDPN) Protein

abx650139-50g 50 µg
EUR 375

Mouse Monoclonal Podoplanin Antibody

TA327727 1 ml Ask for price

anti- Podoplanin antibody

FNab06598 100µg
EUR 702
Description: Antibody raised against Podoplanin

anti- Podoplanin antibody

FNab06599 100µg
EUR 702
Description: Antibody raised against Podoplanin

Mouse Podoplanin (PDPN) CLIA Kit

20-abx493858
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Podoplanin (PDPN) ELISA Kit

abx571749-96tests 96 tests
EUR 943.2

Mouse Podoplanin (PDPN) ELISA Kit

20-abx154564
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Podoplanin (PDPN) ELISA Kit

DLR-PDPN-Mu 96T
EUR 475
Description: tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

DLR-PDPN-Mu-48T 48T
EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

DLR-PDPN-Mu-96T 96T
EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

DL-PDPN-Mu 96T
EUR 453
Description: tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit

EK8596 96Т
EUR 799

Mouse Podoplanin (PDPN) ELISA Kit

EKN47838-48T 48T
EUR 389.62

Mouse Podoplanin (PDPN) ELISA Kit

EKN47838-5x96T 5x96T
EUR 2643.85

Mouse Podoplanin (PDPN) ELISA Kit

EKN47838-96T 96T
EUR 556.6

Mouse Podoplanin (PDPN) ELISA Kit

AE28131MO-48Tests 48 Tests
EUR 325
Description: Mouse (Mus musculus)

Mouse Podoplanin (PDPN) ELISA Kit

AE28131MO-96Tests 96 Tests
EUR 610
Description: Mouse (Mus musculus)

Mouse Podoplanin (PDPN)ELISA kit

YLA0596MO-48T 48T Ask for price

Mouse Podoplanin (PDPN)ELISA kit

YLA0596MO-96T 96T Ask for price

Mouse Podoplanin, Pdpn ELISA KIT

ELI-06723m 96tests
EUR 736

Mouse Podoplanin,PDPN ELISA KIT

E1437Mo-1096T 10*96T
EUR 4122

Mouse Podoplanin,PDPN ELISA KIT

E1437Mo-48wells 48 wells
EUR 300

Mouse Podoplanin,PDPN ELISA KIT

E1437Mo-596T 5*96T
EUR 2061

Mouse Podoplanin,PDPN ELISA KIT

E1437Mo-96wells 96 wells
EUR 458

Mouse Podoplanin (PDPN) ELISA Kit

EKU06727-48T 48T
EUR 571.55

Mouse Podoplanin (PDPN) ELISA Kit

EKU06727-5x96T 5x96T
EUR 3878.38
Brenda


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