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Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases.

Tick-borne nairoviruses (order Bunyavirales) encode an ovarian tumor area protease (OTU) that suppresses the innate immune response by reversing the post-translational modification of proteins by ubiquitin (Ub) and interferon-stimulated gene product 15 (ISG15). Ub is extremely conserved throughout eukaryotes, whereas ISG15 is simply current in vertebrates and reveals substantial sequence variety. Prior makes an attempt to handle the impact of ISG15 variety on viral protein-ISG15 interactions have centered on solely a single species’ ISG15 or a restricted choice of nairovirus OTUs.

To achieve a extra full perspective of OTU-ISG15 interactions, we biochemically assessed the relative actions of 14 various nairovirus OTUs for 12 species’ ISG15 and located that ISG15 exercise is predominantly restricted to specific nairovirus lineages reflecting, on the whole, recognized virus-host associations. To uncover the underlying molecular elements driving OTUs affinity for ISG15, X-ray crystal constructions of Kupe virus and Ganjam virus OTUs sure to sheep ISG15 had been solved and in comparison with complexes of Crimean-Congo hemorrhagic fever virus and Erve virus OTUs sure to human and mouse ISG15, respectively. By means of mutational and structural evaluation seven residues in ISG15 had been recognized that predominantly affect ISG15 species specificity amongst nairovirus OTUs.

Moreover, OTU residues had been recognized that affect ISG15 choice, suggesting the potential for viral OTUs to adapt to completely different host ISG15s. These findings present a basis to additional develop analysis strategies to hint nairovirus-host relationships and delineate the total affect of ISG15 variety on nairovirus an infection.

Substrate-to-Product Conversion Facilitates Energetic Web site Loop Opening in Yeast Enolase: A Molecular Dynamics Examine.

Yeast enolase serves as a prototype for metalloenzymes with labile, catalytic lively website steel ions and is vital for glycolysis and fermentation processes. Herein, microsecond molecular dynamics simulations of the protein-substrate and protein-product complexes are performed to elucidate the mechanism of the opening of catalytically vital lively website loops. These simulations point out that conversion of substrate to product is accompanied by diminished steel coordination and hydrogen-bonding interactions, in addition to enhanced loop flexibility.
Furthermore, free vitality simulations present that the loop opening is endergonic when substrate is sure however exergonic when product is sure. Thus, the conversion to product weakens the affiliation of the loop with the ligand and binding website, thereby facilitating the loop opening after catalysis and enabling product launch. These insights about lively website loop motions in enzyme catalysis could also be helpful in guiding enzyme design efforts. The triterpenes are structurally various group of specialised metabolites with vital roles in plant protection and human well being. Glycyrrhizin, with a carboxyl group at C-30 of its aglycone moiety, is a beneficial triterpene glycoside, the manufacturing of which is restricted to legume medicinal vegetation belonging to the Glycyrrhiza species.
Cytochrome P450 monooxygenases (P450s) are vital for producing triterpene chemodiversity by catalyzing site-specific oxidation of the triterpene scaffold. CYP72A154 was beforehand recognized from the glycyrrhizin-producing plant Glycyrrhiza uralensis as a C-30 oxidase in glycyrrhizin biosynthesis, however its regioselectivity is slightly low. In distinction, CYP72A63 from Medicago truncatula confirmed superior regioselectivity in C-30 oxidation, enhancing the manufacturing of glycyrrhizin aglycone in engineered yeast. The underlying molecular foundation of C-30 product regioselectivity is just not properly understood.

Molecular recognition within the product website of cellobiohydrolase Cel7A regulates processive step size.

Cellobiohydrolase Cel7A is an industrial vital enzyme that breaks down cellulose by a fancy processive mechanism. The enzyme threads the lowering finish of a cellulose strand into its tunnel-shaped catalytic area and progresses alongside the strand whereas sequentially releasing the disaccharide cellobiose. Whereas some molecular particulars of this intricate course of have emerged, normal structure-function relationships for Cel7A stay poorly elucidated. One attention-grabbing side is the prevalence of notably sturdy ligand interactions within the product binding website. On this work, we analyze these interactions in Cel7A from Trichoderma reesei with particular emphasis on the Arg251 and Arg394 residues.
We made intensive biochemical characterization of enzymes that had been mutated in these two positions and confirmed that the arginine residues contributed strongly to product binding. Particularly, about 50% of the full normal free vitality of product binding may very well be ascribed to 4 hydrogen bonds to Arg251 and Arg394, which had beforehand been recognized in crystal constructions. Mutation of both Arg251 or Arg394 lowered manufacturing inhibition of Cel7A, however on the similar time altered the enzyme product profile and resulted in about 50% discount in each processivity and hydrolytic exercise.

Phenol, crystalline

PB4112 500g
EUR 175.28
  • Product category: Biochemicals/Misc. Biochemicals

Phenol, (Carbolic acid) Double distilled for Molecular Biology

PD0252 500g
EUR 160.49
  • Product category: Biochemicals/Misc. Biochemicals

Urea, suitable for molecular biology

GE1210-1KG 1 kg
EUR 89

Urea, suitable for molecular biology

GE1210-500G 500 g
EUR 64

Sucrose, GlenBiol, suitable for molecular biology

GC3201-1KG 1 kg
EUR 75

BCIP (Molecular Biology Grade)

CE108 250 mg
EUR 63

BCIP (Molecular Biology Grade)

CE109 1 g
EUR 90

CHAPS (Molecular Biology Grade)

CE114 1 g
EUR 55

CHAPS (Molecular Biology Grade)

CE115 5 g
EUR 131

CHAPS (Molecular Biology Grade)

CE116 25 g
EUR 410

DAPI (Molecular Biology Grade)

CE117 5 mg
EUR 60

DAPI (Molecular Biology Grade)

CE118 25 mg
EUR 133

DAPI (Molecular Biology Grade)

CE119 100 mg
EUR 319

Dimethylsulfoxide (Molecular Biology Grade)

CE120 100 ml
EUR 55

Dimethylsulfoxide (Molecular Biology Grade)

CE121 500 ml
EUR 92

DTT (Molecular Biology Grade)

CE131 5 g
EUR 78

DTT (Molecular Biology Grade)

CE132 10 g
EUR 111

DTT (Molecular Biology Grade)

CE133 25 g
EUR 203

Glycine (Molecular Biology Grade)

CE158 1 kg
EUR 70

Glycine (Molecular Biology Grade)

CE159 5 kg
EUR 190

HEPES (Molecular Biology Grade)

CE171 100 g
EUR 82

HEPES (Molecular Biology Grade)

CE172 500 g
EUR 224

HEPES (Molecular Biology Grade)

CE173 1 kg
EUR 354

Lysozyme (Molecular Biology Grade)

CE188 1 g
EUR 59

Lysozyme (Molecular Biology Grade)

CE189 10 g
EUR 206

NAD (Molecular Biology Grade)

CE196 1 g
EUR 60

NAD (Molecular Biology Grade)

CE197 5 g
EUR 138

NBT (Molecular Biology Grade)

CE209 1 g
EUR 103

NBT (Molecular Biology Grade)

CE210 5 g
EUR 300

Tris (Molecular Biology Grade)

CE237 500 g
EUR 89

Tris (Molecular Biology Grade)

CE238 1 kg
EUR 128

Tris (Molecular Biology Grade)

CE239 5 kg
EUR 446

Tween20 (Molecular Biology Grade)

CE242 1 l
EUR 89

Water (Molecular Biology Grade)

CE243 500 ml
EUR 52

Water (Molecular Biology Grade)

CE244 1 l
EUR 56

Ammonium sulfate (Molecular Biology Grade)

CE105 250 g
EUR 46

Ammonium sulfate (Molecular Biology Grade)

CE106 1 kg
EUR 60

Ammonium sulfate (Molecular Biology Grade)

CE107 5 kg
EUR 128

Bis-Acrylamid (Molecular Biology Grade)

CE110 50 g
EUR 79

Bis-Acrylamid (Molecular Biology Grade)

CE111 250 g
EUR 216

Formamide deionized (Molecular Biology Grade)

CE145 500 ml
EUR 73

Formamide deionized (Molecular Biology Grade)

CE146 1 l
EUR 100

Glycerol 87 % (Molecular Biology Grade)

CE154 1 l
EUR 78

Glycerol waterfree (Molecular Biology Grade)

CE155 500 ml
EUR 65

Glycerol waterfree (Molecular Biology Grade)

CE156 1 l
EUR 85

Glycerol waterfree (Molecular Biology Grade)

CE157 2.5 l
EUR 142

Guanidine - Hydrochloride (Molecular Biology Grade)

CE160 100 g
EUR 78

Guanidine - Hydrochloride (Molecular Biology Grade)

CE161 250 g
EUR 128

Guanidine - Hydrochloride (Molecular Biology Grade)

CE162 500 g
EUR 194

Guanidine - Hydrochloride (Molecular Biology Grade)

CE163 1 kg
EUR 294

Guanidine Thiocyanate (Molecular Biology Grade)

CE164 100 g
EUR 72

Guanidine Thiocyanate (Molecular Biology Grade)

CE165 500 g
EUR 160

Guanidine Thiocyanate (Molecular Biology Grade)

CE166 1 kg
EUR 256

MOPS buffer (Molecular Biology Grade)

CE194 100 g
EUR 85

MOPS buffer (Molecular Biology Grade)

CE195 250 g
EUR 141

Sodium chloride (Molecular Biology Grade)

CE205 500 g
EUR 52

Sodium chloride (Molecular Biology Grade)

CE206 1 kg
EUR 59

Sodium chloride (Molecular Biology Grade)

CE207 5 kg
EUR 103

D(+)-Sucrose (Molecular Biology Grade)

CE224 500 g
EUR 56

D(+)-Sucrose (Molecular Biology Grade)

CE225 1 kg
EUR 70

D(+)-Sucrose (Molecular Biology Grade)

CE226 5 kg
EUR 173

Tris - Hydrochloride (Molecular Biology Grade)

CE234 250 g
EUR 83

Tris - Hydrochloride (Molecular Biology Grade)

CE235 500 g
EUR 120

Tris - Hydrochloride (Molecular Biology Grade)

CE236 1 kg
EUR 186

TritonX-100 (Molecular Biology Grade)

CE240 500 ml
EUR 56

TritonX-100 (Molecular Biology Grade)

CE241 1 l
EUR 66

Water, Ultrapure Molecular Biology Grade

41024-4L 4L
EUR 121
Description: Minimum order quantity: 1 unit of 4L

Tween 20, Molecular Biology Grade

T9100-010 100ml
EUR 72

Tween 20, Molecular Biology Grade

T9100-050 500ml
EUR 111

Tween 20, Molecular Biology Grade

T9100-100 1L
EUR 134

Water, distilled, GlenBiol™, suitable for molecular biology

GK8512-1L 1 l
EUR 77

Agarose, low EEO, GlenBiol, suitable for molecular biology

GE6258-100G 100 g
EUR 181

Crystalline

5-01010 10mg Ask for price

EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade)

CE135 250 g
EUR 60

EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade)

CE136 500 g
EUR 72

EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade)

CE137 1 kg
EUR 104

EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade)

CE138 5 kg
EUR 349

D(+)-Glucose waterfree (Molecular Biology Grade)

CE148 500 g
EUR 56

D(+)-Glucose waterfree (Molecular Biology Grade)

CE149 1 kg
EUR 63

D(+)-Glucose waterfree (Molecular Biology Grade)

CE150 5 kg
EUR 150

Yeast extract powder (Molecular Biology Grade)

CE169 500 g
EUR 111

Hyaluronidase Grade I (Molecular Biology Grade)

CE174 1 g
EUR 194

Hyaluronidase Grade I (Molecular Biology Grade)

CE175 5 g
EUR 767

Magnesium acetate - Tetrahydrate (Molecular Biology Grade)

CE190 500 g
EUR 82

NADH - Disodium salt (Molecular Biology Grade)

CE198 1 g
EUR 76

NADH - Disodium salt (Molecular Biology Grade)

CE199 5 g
EUR 204

NADP - sodium salt (Molecular Biology Grade)

CE200 250 mg
EUR 77

NADP - sodium salt (Molecular Biology Grade)

CE201 1 g
EUR 159

NADPH - Tetrasodium salt (Molecular Biology Grade)

CE202 25 mg
EUR 59

NADPH - Tetrasodium salt (Molecular Biology Grade)

CE204 500 mg
EUR 312

SSC Buffer (20X) (Molecular Biology Grade)

CE229 1 l
EUR 72

XTT sodium salt (Molecular Biology Grade)

CE250 100 mg
EUR 174

XTT sodium salt (Molecular Biology Grade)

CE251 500 mg
EUR 510

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE100 50 g
EUR 107

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE101 100 g
EUR 161

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE102 250 g
EUR 323

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE103 500 g
EUR 547

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE104 1 kg
EUR 969

EDTA solution pH 8.0 (0.5 M) (Molecular Biology Grade)

CE141 500 ml
EUR 73

LB-Agar - Powder according to Lennox (Molecular Biology Grade)

CE178 500 g
EUR 91

LB-Agar - Powder according to Lennox (Molecular Biology Grade)

CE179 2.5 kg
EUR 251

LB-Agar - Powder according to Miller (Molecular Biology Grade)

CE180 500 g
EUR 87

LB-Agar - Powder according to Miller (Molecular Biology Grade)

CE181 2.5 kg
EUR 246

LB-Medium - Powder according to Lennox (Molecular Biology Grade)

CE182 500 g
EUR 90

LB-Medium - Powder according to Lennox (Molecular Biology Grade)

CE183 2.5 kg
EUR 251

LB-Medium - Powder according to Miller (Molecular Biology Grade)

CE184 2.5 kg
EUR 246

Agarose LE, Ultra-Pure Molecular Biology Grade, 100 g

41028-100G 100G
EUR 222
Description: Minimum order quantity: 1 unit of 100G

Agarose LE, Ultra-Pure Molecular Biology Grade, 25 g

41028-25G 25G
EUR 109
Description: Minimum order quantity: 1 unit of 25G

Agarose LE, Ultra-Pure Molecular Biology Grade, 500 g

41028-500G 500G
EUR 719
Description: Minimum order quantity: 1 unit of 500G

AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 100G PER UNIT

AGR-LE-100 1/pk
EUR 168
Description: Bioscience Mol Bio; Agarose

Phenol

20-abx184753
  • EUR 244.00
  • EUR 217.00
  • 1 kg
  • 500 g
  • Shipped within 1-2 weeks.

AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 500G/UNIT, 10 UNITS PER CASE

AGR-LE-5001 1/pk
EUR 3058
Description: Bioscience Mol Bio; Agarose

AGAROSE MS, PCR SCREENING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE

AGR-MS-1001 1/pk
EUR 2038
Description: Bioscience Mol Bio; Agarose

100 ML, MOLECULAR BIOLOGY GRADE WATER; TESTED TO USP STERILE PURIFIED WATER SPECIFICATIONS

46-000-CI 100 mL/pk
EUR 57
Description: Media Catalog; Sterile Wi-Fi Qual, Cell

1 L, MOLECULAR BIOLOGY GRADE WATER; TESTED TO USP STERILE PURIFIED WATER SPECIFICATIONS

46-000-CM 1L/pk
EUR 98
Description: Media Catalog; Sterile Wi-Fi Qual, Cell

500 ML, MOLECULAR BIOLOGY GRADE WATER; TESTED TO USP STERILE PURIFIED WATER SPECIFICATIONS

46-000-CV 500 mL/pk
EUR 106
Description: Media Catalog; Sterile Wi-Fi Qual, Cell

AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 100G PER UNIT, 10 UNITS PER CASE

AGR-LE-1001 1/pk
EUR 772
Description: Bioscience Mol Bio; Agarose

AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE (AL)

AGR-LM-1001 1/pk
EUR 3737
Description: Bioscience Mol Bio; Agarose

AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 50G/UNIT, 10 UNITS PER CASE (AL)

AGR-LM-501 1/pk
EUR 2075
Description: Bioscience Mol Bio; Agarose

Crystalline [H-Trp-Gly-OH; MW: 261.2]

SP-55342-1 1 mg
EUR 141

Nonyl Phenol

AG037 1 mg
EUR 523

Nonyl Phenol

AT037 1mg
EUR 1368

Phenol Red

GT9844-100G 100 g
EUR 110

Phenol Red

GT9844-250G 250 g
EUR 181

Phenol Red

GT9844-25G 25 g
EUR 62

Phenol Red

GT9844-5G 5 g
EUR 46

Phenol, 99%

GK6990-100G 100 g
EUR 44

Phenol, 99%

GK6990-1KG 1 kg
EUR 78

Phenol, 99%

GK6990-500G 500 g
EUR 56

Water Phenol

abx082109-250ml 250 ml
EUR 189
  • Shipped within 5-10 working days.

Phenol red

PB0420 25g
EUR 70.88
  • Product category: Culture Media/Indicators/Stains

ELISA kit for Human PST (Phenol Sulfotransferase)

ELK3246 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Phenol Sulfotransferase (PST). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Phen
  • Show more
Description: A sandwich ELISA kit for detection of Phenol Sulfotransferase from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse PST (Phenol Sulfotransferase)

ELK3642 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Phenol Sulfotransferase (PST). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Phen
  • Show more
Description: A sandwich ELISA kit for detection of Phenol Sulfotransferase from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Rat PST (Phenol Sulfotransferase)

ELK6740 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Phenol Sulfotransferase (PST). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Phen
  • Show more
Description: A sandwich ELISA kit for detection of Phenol Sulfotransferase from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Phenol Red Solution

CA013-010 100ml
EUR 69

4-(Benzyloxy)phenol

GP9986-100G 100 g
EUR 118

4-(Benzyloxy)phenol

GP9986-250G 250 g
EUR 198

4-(Benzyloxy)phenol

GP9986-25G 25 g
EUR 59

Phenol, 4-propoxy-

20-abx184303
  • EUR 523.00
  • EUR 286.00
  • 125g
  • 25 g
  • Shipped within 1-2 weeks.

2-(Aminomethyl)phenol

20-abx185699
  • EUR 314.00
  • EUR 1442.00
  • EUR 592.00
  • 1 g
  • 25 g
  • 5 g
  • Shipped within 1-2 weeks.

3-(Aminomethyl)phenol

20-abx185751
  • EUR 425.00
  • EUR 2277.00
  • EUR 857.00
  • 1 g
  • 25 g
  • 5 g
  • Shipped within 1-2 weeks.

Phenol, saturated (pH7.9)

PC6910 100ml
EUR 76.1
  • Product category: Biochemicals/Solvents

Phenol, saturated (pH4.5)

PC6920 100ml
EUR 76.1
  • Product category: Biochemicals/Solvents

30UL CLEAR PIPET TIPS FOR MOLECULAR DEVICE LIBERTY.

LT-384-R 3840/pk
EUR 2193
Description: Robotic Tips; Robotic tips - Axygen

Ceraplex , No Phenol red

C3320-050 500ml Ask for price

Phenol Red (sodium salt)

HY-D0169A 500mg
EUR 108

Phenol Red sodium salt

GT6682-100G 100 g
EUR 142

Phenol Red sodium salt

GT6682-25G 25 g
EUR 70

Phenol Red sodium salt

GT6682-5G 5 g
EUR 44

Folin & Ciocalteu’s phenol reagent

abx082175-50ml 50 ml
EUR 189
  • Shipped within 5-10 working days.

Phenol Sulfotransferase (PST) Antibody

20-abx129668
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Phenol Sulfotransferase (PST) Antibody

20-abx102281
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Phenol Sulfotransferase (PST) Antibody

20-abx102282
  • EUR 439.00
  • EUR 133.00
  • EUR 1247.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

2,6-Bis(Trifluoromethyl)Phenol

abx188185-5g 5 g
EUR 2527
  • Shipped within 1-2 weeks.

3,5-Bis(Trifluoromethyl)Phenol

abx188331-5g 5 g
EUR 314
  • Shipped within 1-2 weeks.

Phenol Sulfotransferase (PST) Antibody

20-abx174014
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug
  • Please enquire.

Phenol Sulfotransferase (PST) Antibody

20-abx174015
  • EUR 871.00
  • EUR 453.00
  • 1 mg
  • 200 ug
  • Please enquire.

Phenol Sulfotransferase (PST) Antibody

20-abx177976
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.

PHENOL RED BROTH BASE

P16-104-10kg 10 kg
EUR 899

PHENOL RED BROTH BASE

P16-104-2kg 2kg
EUR 234

PHENOL RED BROTH BASE

P16-104-500g 500 g
EUR 100

PHENOL RED DEXTROSE BROTH

P16-105-10kg 10 kg
EUR 743

PHENOL RED DEXTROSE BROTH

P16-105-2Kg 2 Kg
EUR 200

PHENOL RED DEXTROSE BROTH

P16-105-500g 500 g
EUR 90

PHENOL RED LACTOSE BROTH

P16-121-10kg 10 kg
EUR 1254

PHENOL RED LACTOSE BROTH

P16-121-2Kg 2 Kg
EUR 312

PHENOL RED LACTOSE BROTH

P16-121-500g 500 g
EUR 121

PHENOL RED MANNITOL BROTH

P16-122-10kg 10 kg
EUR 1563

PHENOL RED MANNITOL BROTH

P16-122-2kg 2kg
EUR 379

PHENOL RED MANNITOL BROTH

P16-122-500g 500 g
EUR 139

PHENOL RED SUCROSE BROTH

P16-123-10kg 10 kg
EUR 835

PHENOL RED SUCROSE BROTH

P16-123-2Kg 2 Kg
EUR 221

PHENOL RED SUCROSE BROTH

P16-123-500g 500 g
EUR 96

Recombinant Phenol Sulfotransferase (PST)

4-RPB268Hu01
  • EUR 481.70
  • EUR 232.00
  • EUR 1531.36
  • EUR 577.12
  • EUR 1054.24
  • EUR 385.00
  • EUR 3678.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P50225
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 35.6kDa
  • Isoelectric Point: Inquire
Description: Recombinant Human Phenol Sulfotransferase expressed in: E.coli
The place of the 2 arginine residues intently matches the two-fold screw axis symmetry of the substrate, and this energetically favors the productive enzyme-substrate complicated. Our outcomes point out that the sturdy and particular ligand interactions of Arg251 and Arg394 present a easy proofreading system that controls the step-length throughout consecutive hydrolysis and minimizes lifeless time related to transient, non-productive complexes.

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